James Phillips is selected to start in the back row, while hooker Mark Regan is named on the bench for his last game for the club.
Head coach Paul Hull said: “Leicester are at the top of the league and are guaranteed a home slot but I'm sure they'll want to stay top. They will want to keep some momentum leading into their Heineken Cup semi-final. Their motivation will be high.
“We're now relegated so we're motivated for different reasons, for example, it will be the last game in a Bristol shirt for a few players.
“We always expect a physical game against Leicester, so we’ve reflected that in our split on the bench.”
Tickets for Saturday’s game are available now from the Tigers ticket office. Contact 0844 856 1880 or call in at Welford Road.
Bristol Rugby (v Leicester Tigers, Walkers Stadium, Saturday 3pm)
15 Luke Arscott
14 Lee Robinson
13 Luke Eves
12 Junior Fatialofa
11 David Lemi
10 Ed Barnes
9 Shaun Perry
1 Mark Irish
2 Scott Linklater
3 Darren Crompton
4 Mariano Sambucetti
5 Robert Sidoli
6 James Phillips
7 Redford Pennycook
8 Dan Ward-Smith
Replacements
16 Mark Regan
17 Wayne Thompson
18 Roy Winters
19 Chevvy Pennycook
20 Matt Salter
21 Haydn Thomas
22 Greg Barden