Danny Cipriani and Dominic Waldouck, who both started last week, take a turn on the bench.
The team includes England internationals Tom Voyce, James Haskell and Tom Palmer, and will be led by flanker John Hart.
Director of rugby Ian McGeechan said: "Facing Leicester Tigers is always a big game, and Sunday will be a massive challenge for us. We had a good hour in the middle of the game last week, when I was very pleased with our all-round game, but we are now looking for a big game over 80 minutes. That's the only way to put yourself in a position to beat sides like Leicester."
Tickets for Sunday's game are still available from the Wasps ticket hotline on 0870 414 1515 or online at http://www.wasps.co.uk/
London Wasps team (vs Leicester Tigers, at Adams Park, Sunday 3.00pm)
15 Mark Van Gisbergen
14 Chris Bishay
13 Fraser Waters
12 Riki Flutey
11 Tom Voyce
10 Dave Walder
9 Mark McMillan
1 Tim Payne
2 Joe Ward
3 Pat Barnard
4 George Skivington
5 Tom Palmer
6 John Hart (c)
7 James Haskell
8 Richard Birkett
Replacements
16 James Buckland
17 Michael Holford
18 Hugo Ellis
19 Dan Leo
20 Simon Amor
21 Dominic Waldouck
22 Danny Cipriani