Coach Allen Clarkes side includes Heineken Cup winners Denis Hurley and Tomás O'Leary as well as Leinster's Magners League winner Jonathan Sexton.
This is Murphys second experience of the Churchill Cup tournament after playing in last years event won by England Saxons at Twickenham.
Ireland A (v USA, Wednesday, June 11):
15 Denis Hurley (Cork Constitution/Munster), 14 Mark McCrea (Malone/Ulster), 13 Kieran Lewis (Garryowen/Munster), 12 Keith Earls (Garryowen/Munster), 11 Brian Tuohy (Cornish Pirates), 10 Johnathan Sexton (St Mary's College/Leinster), 9 Tomas O'Leary (Dolphin/Munster); 1 Cian Healy (Clontarf/Leinster), 2 Denis Fogarty (Cork Constitution/Munster), 3 Michael Ross (Harlequins), 4 Bob Casey (London Irish, captain), 5 Ryan Caldwell (Dungannon/Ulster), 6 Neil Best (Belfast Harlequins/Ulster), 7 Johnny O'Connor (Corinthians/Connacht), 8 Roger Wilson (Belfast Harlequins/Ulster).
Replacements: 16 Tom Court (Malone/Ulster), 17 Sean Cronin (Shannon/Munster), 18 Trevor Hogan (Shannon/Leinster), 19 Donnacha Ryan (Shannon/Munster), 20 David Pollock (Dungannon/Ulster), 21 Frank Murphy (Leicester Tigers), 22 Ian Keatley (Clontarf/Leinster)