Harry Wells has been called into the starting side to partner Cameron Henderson in the second row.
He replaces Ollie Chessum, while Côme Joussain has been brought on to the bench.
The matchday squad is otherwise unchanged.
STARTING XV
15 Freddie Steward [102]
14 Adam Radwan [3]
13 Solomone Kata [35]
12 Joseph Woodward [24]
11 Ollie Hassell-Collins [39]
10 Handré Pollard [45]
9 Jack van Poortvliet [87]
1 Nicky Smith [15]
2 Julián Montoya [70]
3 Joe Heyes [155]
4 Cameron Henderson [56]
5 Ollie Chessum [61]
6 Hanro Liebenberg [123]
7 Tommy Reffell [129]
8 Olly Cracknell [58]
REPLACEMENTS
16 Charlie Clare [115]
17 James Whitcombe [65]
18 Dan Cole [336]
19 Harry Wells [214]
20 Emeka Ilione [39]
21 Ben Youngs [329]
22 Jamie Shillcock [44]
23 Izaia Perese [12]