11 Leicester Tigers players will represent their countries this weekend across the Autumn Nations Series and for England A' against Australia.
Catch the Autumn Nations series live on TNT Sports, with new Investec Champions Cup broadcasters, Premier Sports, showing the England A' fixture at 2pm.
Academy graduate duo Jack van Poortvliet and Freddie Steward return to the England matchday squad against Tigers flyhalf Handre Pollard and the Springboks.
George Martin retains his place in England's second-row with Dan Cole also named on the bench.
Tight head prop Will Hurd starts for Scotland against Portugal, his second start in the test rugby arena. Fellow front-rower Joe Heyes will wear number three for England A' against Australia A' with Jamie Shillcock among the replacements.
Nick Smith and Tommy Reffell will also start from the bench in Wales' clash against the Wallabies, while Tigers captain Julian Montoya leads Los Pumas against Ireland on Friday night.
Ireland vs Argentina
8pm Friday, TNT Sports
Scotland vs Portugal
3pm Saturday, TNT Sports
England vs South Africa
5.40pm Saturday, TNT Sports
England A' vs Australia A'
2pm Sunday, Premier Sports